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Publications

Arthritis and Immunology Research Program

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Hiding in Plain Sight: OMRF researchers discover rogue immune cells in healthy adults

A. Darise Farris, Ph.D. Associate Member, Arthritis and Immunology Research Program Adjunct Associate Professor, Departments of Microbiology & Immunology and   Pathology, University of Oklahoma Health Sciences Center

Recent Publications
Pan ZJ, Meier S, Schwarz K, Azbill J, Akira S, Uematsu S, Farris AD. TLR7 modulates anti-nucleosomal autoantibody isotype and renal complement deposition in mice exposed to syngeneic late apoptotic cells. Ann Rheum Dis, 2009. [Abstract] EPub

Duty JA, Szodoray P, Zheng NY, Koelsch KA, Zhang Q, Swiatkowski M, Mathias M, Garman L, Helms C, Nakken B, Smith K, Farris AD, Wilson PC. Functional anergy in a subpopulation of naive B cells from healthy humans that express autoreactive immunoglobulin receptors. J Exp Med 206:139-151, 2009. [Abstract]

Nguyen ML, Crowe SR, Kurella S, Teryzan S, Cao B, Ballard JD, James JA, Farris AD. Sequential B cell epitopes of Bacillus anthracis Lethal Factor bind lethal Toxin-neutralizing antibodies. Infect Immun 77:162-169, 2009. [Abstract]

Selected Publications
Maeda K, Malykhin A, Teague-Weber BN, Sun XH, Farris AD, Coggeshall KM. Interleukin 6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosis-prone B6.Sle1.Yaa animals. Blood 113:4534-4540, 2009. [Abstract]

Dudek NL, Maier S, Chen ZJ, Mudd PA, Mannering SI, Jackson DC, Zeng W, Keech CL, Hamlin K, Pan ZJ, vis-Schwarz K, Workamn-Azbel J, Bachmann M, McCluskey J, Farris AD. T cell epitopes of the La/SSb autoantigen in humanized transgenic mice expressing the hLa class II haplotype DRB1*0301/DQB1*0201. Arthritis Rheum 56:3387-3398, 2007. [Abstract]

Kurella S, Yaciuk JC, Dozmorov I, Frank MB, Centola M, Farris AD. Transcriptional modulation of TCR, Notch and Wnt signaling pathways in SEB-anergized CD4+ T cells. Genes Immun Oct;6(7):596-608, 2005. [Abstract]

Keech CL, Farris AD, Beroukas D, Gordon TP, McCluskey J. Cognate T cell help is sufficient to trigger anti-nuclear autoantibodies in naive mice. J Immunol 166: 5826-34, 2001. [Abstract]

Farris AD, Brown L, Reynolds P, Harley JB, James JA, Scofield RH, McCluskey J, Gordon TP. 1999. Induction of autoimmunity by multivalent immunodominant and subdominant T cell determinants of La (SS-B). J Immunol 162: 3079-87, 1999. [Abstract]