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Publications

Cardiovascular Biology Research Program

Dr. Esmon In The News

OMRF scientists discover promising new path for treating traumas

OMRF drug wins national award

Charles T. Esmon, Ph.D. Member, Cardiovascular Biology Research Program Lloyd Noble Chair in Cardiovascular Biology Member, National Academy of Sciences Investigator, Howard Hughes Medical Institute Adjunct Professor, Departments of Biochemistry & Molecular Biology and   Pathology, University of Oklahoma Health Sciences Center

Recent Publications
Van Sluis GL, Niers TM, Esmon CT, Tigchelaar W, Richel DJ, Buller HR, Van Noorden CJ, Spek CA.  Endogenous activated protein C limits cancer cell extravasation through sphingosine-1-phosphate receptor 1 mediated vascular endothelial barrier enhancement.  Blood 2009. [Abstract]  EPub

Brooks EG, Trotman W, Wadsworth MP, Taatjes DJ, Evans MF, Ittleman FP, Callas PW, Esmon CT, Bovill EG.  Valves of the deep venous system: an overlooked risk factor. Blood 2009. [Abstract] EPub

Finigan JH, Boueiz A, Wilkinson E, Damico R, Skirball J, Pae HH, Damarla M, Hasan E, Pearse DB, Reddy SP, Grigoryev DN, Cheadle C, Esmon CT, Garcia JG, Hassoun PM. Activated Protein C protects against ventilator-induced pulmonary capillary leak. Am J Physiol Lung Cell Mol Physiol 296:L1002-L1011, 2009. [Abstract]

Selected Publications
Li Z, Wells CW, Esmon CT, Zhao M. Phosphatidylethanolamine at the endothelial surface of aortic flow dividers. J Thromb Haemost 7:227-229, 2008. [Abstract]

Zheng X, Li W, Song Y, Hu Y, Ferrell GL, Esmon NL, Esmon CT. Non-hematopoietic EPCR regulates the coagulation and inflammatory responses during endotoxemia. J Thromb Haemost 5:1394-1400, 2007. [Abstract]

Qu D, Wang Y, Song Y, Esmon NL, Esmon CT. The Ser219-->Gly dimorphism of the endothelial protein C receptor contributes to the higher soluble protein levels observed in individuals with the A3 haplotype. J Thromb Haemost 4:229-235, 2006. [Abstract]

Li W, Zheng X, Gu J, Hunter J, Ferrell GL, Lupu F, Esmon NL, Esmon CT. Overexpressing endothelial cell protein C receptor alters the hemostatic balance and protects mice from endotoxin. J Thromb Haemost 3:1351-1359, 2005. [Abstract]

Li W, Zheng X, Gu JM, Ferrell GL, Brady M, Esmon NL, Esmon CT. Extraembryonic expression of EPCR is essential for embryonic viability. Blood 106:2716-2722, 2005. [Abstract]

Ludeman MJ, Kataoka H, Srinivasan Y, Esmon N, Esmon CT, Coughlin SR. PAR1 cleavage and signaling in response to activated protein C and thrombin. J Biol Chem 280:13122-13128, 2005. [Abstract]