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Dr. Westmuckett:

Dr. Westmuckett's profile

Dr. Westmuckett's CV in brief

Publications

Cardiovascular Biology Research Program

Current Publications
Borghei A, Ouyang YB, Westmuckett AD, Marcello MR, Landel CP, Evans JP, Moore KL. Targeted disruption of tyrosylprotein sulfotransferase-2, an enzyme that catalyzes post-translational protein tyrosine O-sulfation, causes male infertility. J Biol Chem 281:9423-9431, 2006. [Abstract]

Lupu C, Westmuckett AD, Peer G, Ivanciu L, Zhu H, Taylor FB, Jr., Lupu F. Tissue factor-dependent coagulation is preferentially up-regulated within arterial branching areas in a baboon model of Escherichia coli sepsis. Am J Path 167:1161-1172, 2005. [Abstract]

Xia L, Ju T, Westmuckett A, An G, Ivanciu L, McDaniel JM, Lupu F, Cummings RD, McEver RP. Defective angiogenesis and fatal embryonic hemorrhage in mice lacking core 1-derived O-glycans. J Cell Biol 164:451-459, 2004. [Abstract]

Selected Publications
Westmuckett AD, Hamuro T, Kakkar VV, Lupu F, Lupu C. Bemiparin and fluid flow modulate the expression, activity and release of tissue factor pathway inhibitor in human endothelial cells in vitro. Thromb Haemost 86(6):1547-54, 2001. [Abstract]

Westmuckett AD, Lupu C, Roquefeuil S, Krausz T, Kakkar VV, Lupu F. Fluid flow induces the upregulation of the synthesis and release of tissue factor pathway inhibitor in vitro. Arterioscler Thromb Vasc Biol 20:2474-2482, 2000. [Abstract]

Westmuckett AD, Lupu C, Goulding D, Das S, Kakkar VV, Lupu F. In situ analysis of tissue factor-dependent thrombin generation in human atherosclerotic vessels. Thromb Haemost 84:904-911, 2000. [Abstract]

Crawley J, Lupu F, Westmuckett AD, Severs N, Kakkar VV, Lupu C. Expression, localization and activity of tissue factor pathway inhibitor in normal and atherosclerotic human vessels. Arterioscler Thromb Vasc Biol 20:1362-1373, 2000. [Abstract]

Lupu C, Poulsen E, Roquefeuil S, Westmuckett AD, Kakkar VV, Lupu F. Cellular effects of heparin on the production and release of tissue factor pathway inhibitor in human endothelial cells in culture. Arterioscler Thromb Vasc Biol 19:2251-2262, 1999. [Abstract]

Lupu C, Goodwin CA, Westmuckett AD, Emis JJ, Scully MF, Kakkar VV, and Lupu F. Tissue factor pathway inhibitor in endothelial cells colocalizes with glycolipid microdomains/caveolae: Regulatory mechanism(s) of the anticoagulant properties of the endothelium. Arterioscler Thromb Vasc Biol 17(11):2964-2974, 1997. [Abstract]